Buckminsterfullerenols as Neuroprotective Agents Against Neuronal Damage

Buckminsterfullerenols as Neuroprotective Agents Against Neuronal Damage A research study published in Neuroscience in 1996 by Dugan et al. investigates the potential of buckminsterfullerenols, a type of water-soluble, polyhydroxylated C60 fullerene derivatives, to protect brain cells (neurons) from damage caused by excitotoxicity and apoptosis. The study demonstrates that these fullerene-based compounds act as powerful antioxidants, […]

Carbon 60’s Potential Health Benefits: A Simple Look at the Science

Carbon 60’s Potential Health Benefits: A Simple Look at the Science A 2008 study in Biomaterials (Markovic et al.) dives into how Carbon 60 (C60), a unique soccer ball-shaped molecule, could support health by managing harmful molecules in the body called free radicals. C60 acts like a “sponge,” soaking up these free radicals, which can […]

Carboxyfullerenes as Potent Neuroprotective Agents

Carboxyfullerenes as Potent Neuroprotective Agents A pioneering study published in the Proceedings of the National Academy of Sciences (Dugan et al., 1997) investigated the neuroprotective potential of water-soluble carboxylic acid C60 derivatives, specifically two regioisomers (C3 and D3 symmetry) with three malonic acid groups per molecule. Using electron paramagnetic resonance (EPR) analysis, both isomers demonstrated […]

Carboxyfullerene SOD Mimetic Enhances Cognition and Lifespan in Mice

Carboxyfullerene SOD Mimetic Enhances Cognition and Lifespan in Mice A groundbreaking study published in Neurobiology of Aging (Quick et al., 2006) explored the effects of a synthetic superoxide dismutase (SOD) mimetic, a small-molecule antioxidant, on aging in wild-type mice. Starting at middle age, mice received chronic treatment with a carboxyfullerene-based compound designed to combat oxidative […]