C60 was found to maintain bone health and mineral density. Use of fullerenes for the treatment of mast cell and basophil-mediated disease 

• Study strengths: US Patent granted
• Study weaknesses: This study was done with human cells in vitro, in a test tube.

C60 protected cartilage cells from aging prematurely or dying off and increased cartilage production by reducing the enzymes that can destroy it. Water-soluble C60 fullerene prevents degeneration of articular cartilage in osteoarthritis via down-regulation of chondrocyte catabolic activity and inhibition of cartilage degeneration during disease development

• Study strengths: They also found positive results when C60 was injected in rabbits. So likely positive results would be found in humans.
• Study weaknesses: This study found positive results with C60 in human cells (in vitro), not confirmed with living humans.