Particles of C60 suspended in oil caused DNA damage in rats, changing the DNA expression of the lungs and liver. Oxidatively Damaged DNA in Rats Exposed by Oral Gavage to C60 Fullerenes and Single-Walled Carbon Nanotubes

• Study strengths: None. Not relevant to C60 that would be consumed by humans.
• Study weaknesses: This study uses nanoparticles of C60, not singly dissolved molecules. Nanoparticles of C60 have never been shown to have any health benefits. In fact, nanoparticles of any substance can have negative effects on health. Only singly dissolved molecules of C60 are shown to be beneficial. In this study, C60 particles were sprayed directly into the lungs of rats and inflammation occurred. Eugenol mitigated acute lung but not spermatic toxicity of C60 fullerene emulsion in mice