Nerves can die from oxidative stress and overstimulation. In this study, C60 protected nerves from dying due to “overwork” in cell cultures. Buckminsterfullerenol free radical scavengers reduce excitotoxic and apoptotic death of cultured cortical neurons

• Study strengths: Strongly protected human nerve cells from oxidative stress and overstimulation.
• Study weaknesses: This study was done with human cells in vitro, in a test tube.

C60 protects neurons from SOD, a reactive oxidative species (free radical), associated with tissue injury and inflammation. SOD activity of carboxyfullerenes predicts their neuroprotective efficacy: A structure-activity study

• Study strengths: Theoretically C60 strongly protective.
• Study weaknesses: Computer simulation, no real experimentation.